Tadeus Reichstein
(Quarles van Ufford) was born on
July 20, 1897 in Wloclawek, Poland. The family moved to Switzerland in
1906. Educated in Zurich, he held posts in the department of organic chemistry
at the Federal Institute of Technology, Zurich, from 1930. From 1946 to
1967 he was professor of organic chemistry at the University of Basel.
He died on August 1, 1996 in Basel, Switzerland.
He gained his scientific
merits in many fields of research such as total synthesis of ascorbic
acid, structure elucidation of steroid hormones, namely aldosteron,
and his leading research in the chemistry of cardiac glycosides, just
to mention a few of his research topics. The field of secondary plant
products brought him back to the neighbouring area of botany and plant
taxonomy. He made a contribution to the studies of structure and properties
of sugars, vitamins, steroids, and cardiac glucosides contained in plants.
He studied
the structure of hormones in the adrenal glands and isolated various
biologically active substances. Apart from hormone research, he was
the first who artificially synthesizes vitamin C (ascorbic acid) - first
vitamin synthesis (1933), a feat achieved about the same time in England
by Sir Walter N. Haworth and co-workers. He also laid the foundation
for the industrial production of Vitamin C. In 1936 he isolated cortisone,
adrenocorticotropic hormone, ACTH and some others hormones of suprarenal
gland. Reichstein's researches on steroids, particularly on hormones
of the adrenal cortex, paralleled those of Kendall in the United States;
his "substance F," described and named by him in 1936, proved identical
to Kendall's "compound E," or cortisone. Cortisone is now used to treat
conditions ranging from skin rash to joint disorders. ACTH is a widely-used
drug to treat rheumatoid arthritis.
In 1947 Tadeus
Reichstein received the Honorary Doctorate of the Sorbonne, Paris. Tadeus
Reichstein, Philip Showalter Hench and
Edward Calvin Kendall, shared
in 1950 Nobel Prize in Medicine for their discoveries relating to the
hormones of the adrenal cortex, their structure and biological effects.
He was a member of Swiss Academy of Medicine (1951) and London Royal
Society (1952). Reichstein was awarded the Copley Medal of the British
Royal Society in 1968. In 1971 Tadeus Reichstein became an Honorary
Member of the Society for Medicinal Plant Research.
Since being
made Emeritus Professor in 1967 he has worked full-time on ferns. His
interests were wide-ranging and global. Tadeus Reichstein was in correspondence
with pteridologists from many parts of the world. His fascination was
for polyploid fern complexes, but he also has spent many years working
on the pteridophytes for Flora Iranica. He continued to use his
expertise in organic chemistry in the investigation of phloroglucinols
in Dryopteris. In all his fern work he was a great collaborator,
and practically all his fern papers have been multi-authored. An exception
is a favourite subject, his 1981 paper on "Hybrids in European Aspleniaceae
(Pteridophyta)", Bot. Helv. 91: 89-139.
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