Nucleophilic Addition to Carbonyl Groups generally takes the
following form:
General Mechanism: The nucleophile attacks the partially positive carbonyl group, chasing the electrons onto the Oxygen. Subsequent protonation yields the alcohol.
Variety of
Nucleophiles:
- Grignard Reagents
- Alcohols
- Amines
- Alkyl Lithium Reagents
- Acetylide Ions
Example of Nucleophilic Addition to Carbonyl Groups:
