Themes > Science > Life Sciences > General Biology > Physiology > The Excretory System > Nitrogen Wastes

Nitrogen wastes are a by product of protein metabolism. Amino groups are removed from amino acids prior to energy conversion. The NH2 (amino group) combines with a hydrogen ion (proton) to form ammonia (NH3).

Ammonia is very toxic and usually is excreted directly by marine animals. Terrestrial animals usually need to conserve water. Ammonia is converted to urea, a compound the body can tolerate at higher concentrations than ammonia. Birds and insects secrete uric acid that they make through large energy expenditure but little water loss. Amphibians and mammals secrete urea that they form in their liver. Amino groups are turned into ammonia, which in turn is converted to urea, dumped into the blood and concentrated by the kidneys.


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